Optimizing treatment selection of severe mental disorders (SMD)

  • Applicant: Dominic Oliver
  • Project ID: 22-090

Currently, there are limited guidelines for selecting a specific medication for a given patient based on their individual characteristics. This study will investigate whether new prediction modelling techniques (precision treatment rules) and electronic health record data can be used to produce a treatment recommendation system that can aid individualised prescriptions for patients with severe mental disorders (psychosis, unipolar depression, and bipolar disorder) to reduce risk of side effects, hospitalisation and suicide.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

About

The Clinical Record Interactive Search has been developed in collboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC