Cardiometabolic and inflammatory changes in serious mental illness: descriptive and predictive work, including genetic associations.

People experiencing serious mental illness – particularly depression and schizophrenia – show higher levels of inflammatory and fat-related measures than similar people from the general population. In future research we want to update data linkages between CRIS and pre-approved research from the GAP study and the wider BioResource database to investigate why people with a serious mental illness, in particular schizophrenia, die earlier than people without one, and if their genetic make-up can help us predict how well people will do.