The effectiveness of modafinil to treat the clozapine caused sedation

  • Applicant: Xin Liu
  • Project ID: 16-024

There is no effective medicine to treat sedation, which is one of the side effects of clozapine. Modafinil has been considered, but has not been fully investigated. We will use the CRIS database to identify cases where modafinil has been combined with clozapine, followed by a case by case manual review on potential efficacy in order to inform further research.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

About

The Clinical Record Interactive Search has been developed in collaboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC