Evaluating changes in creatine phosphokinase (CPK) following clozapine initiation

  • Applicant: Olubanke Dzahini
  • Project ID: 18-084

CPK, a marker of muscle breakdown, may increase following clozapine initiation but the magnitude and significance of these changes are not fully understood. This project aims to examine the patterns of increase in CPK following clozapine initiation and if these changes are useful in diagnosing serious adverse effects of clozapine.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

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The Clinical Record Interactive Search has been developed in collaboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC