TMS-EEG and cognitive tasks to predict antipsychotic treatment response in First Episode Psychosis

Around one-third of people with psychosis do not respond very well to the treatment of antipsychotic medication and continue to have psychotic symptoms, but there is currently no way to predict this which results in many trials of medications and side effects. We will use a technique called Transcranial Magnetic Stimulation and record brain activity using electroencephalography (‘TMS-EEG’) to better understand why some people do not respond to antipsychotics.