Association between antidepressants prescribing, oral anticoagulants and risk of bleeding

  • Applicant: Christoph Mueller
  • Project ID: 20-062

Anticoagulation (blood-thinning) is recommended in patients with irregular heart rhythms to prevent stroke. Newer blood thinners, called direct oral anticoagulants, have been recommended for this since 2014. However, antidepressants are not allowed to be used in conjunction with these as this could increase the risk of bleeding. This study aims to examine whether there is an increased risk of bleeding in those taking newer blood thinners and antidepressants together.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

About

The Clinical Record Interactive Search has been developed in collaboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC