Borrowing Strength from Clinical Trials for Analysing Longitudinal Observational Data: A Bayesian Mixed Model Approach for Investigating Effectiveness of Acetylcholinesterase Inhibitors in Dementia Patients

  • Applicant: Ruth Young
  • Project ID: 14-090

This project investigates the large number of dementia patients who have received acetylcholinesterase inhibitors (AChEIs) over periods of up to nine years, combine this CRIS data with the results of randomised controlled trials of the same drugs in order to compare different drugs within this group.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

About

The Clinical Record Interactive Search has been developed in collboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC