Improving the safety of prescribing in dementia- Clinical validation of the AEC scale

  • Applicant: Delia Bishara
  • Project ID: 18-108

Anticholinergic drugs can increase the risk of cognitive decline, dementia and death in older adults and their use should be limited in this group of patients where possible. The Anticholinergic Effect on Cognition (AEC) scale has been developed in order to rank drugs by the extent of their anticholinergic effects on cognition; and by clinically validating this tool, its use should improve the safety of prescribing in dementia and thus improve health outcomes for patients.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

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The Clinical Record Interactive Search has been developed in collaboration with:

South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC