Investigating clozapine-related blood dyscrasias (neutropenia and agranulocytosis)

  • Applicant: Hamilton Morrin
  • Project ID: 24-023

Clozapine is a highly effective medication used for treatment resistant psychosis though can sometimes be associated with side effects of changes in white blood cell levels. Using a technique developed to identify clozapine treatment start dates, we will investigate who develops these changes in white blood cells and the point at which these changes tend to occur during a course of treatment.

The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.

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South London and Maudsley NHS Foundation Trust
NIHR Maudsley BRC