The DECIDE Study- Decision-Making Capacity in Deciding to Enrol in Research in Psychosis Study | C4C

Decision-Making Capacity can be impaired by psychosis, but we do not know how commonly people in hospital lack Decision-Making Capacity for Research (DMC-R). Is it safe to recruit to recruit in this setting? How can we ensure that consent to participate in biomedical research is valid in inpatients with psychosis, and how can we support people with psychosis to make decisions about biomedical research? The DECIDE Study will look at the ability of people admitted to a psychiatric hospital with psychosis to make a decision about participating in medical research. We know that when people are unwell with psychosis it can affect their ability to make decisions. People may be keen to participate, but excluded because they are assumed by health professionals to be unable to make an informed decision about participation. The study will recruit people with psychosis who are unwell in hospital to find out what percentage of people might actually be able to make this decision when unwell and explore the associated features. It will explore patients and their families views on the current regulations around research, and possible ways to help people make decisions. We will use this information to design a way to support decision-making about research participation, and to develop guidance for Research Ethics Committees, researchers, patients and the public on research participation in people with psychosis. This will help make research more inclusive and relevant to people with psychosis, and ensure it is safe to recruit people for research who are admitted to hospital.