Search the CRIS Projects
Welcome to the CRIS project search area. As you will see below, there are a number of ways to find information about our CRIS projects. Simply add the criteria you are looking for into the relevant search field to see the relevant projects.
Please contact the CRIS Administrator for further details on existing projects or to apply to use CRIS for your own study. Email: cris.administrator@slam.nhs.uk
Psychotic episodes associated with the menstrual cycle
Approximately 200 possible cases of psychotic episodes linked to the menstrual cycle have been reported in the scientific literature. We will attempt to identify further cases and describe their characteristics.
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Reading between the lines: How the wording of clinical formulations could influence the care provided to patients with personality disorder
This project aims to investigate the relationship between clinical outcomes in personality disorder and the presence of negative patient descriptors in clinical notes.
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Cannabis withdrawal and admission to PICU
Many patients with psychosis use cannabis. If they are admitted to hospital, they are no longer able to access the drug. Cannabis withdrawal can cause symptoms such as insomnia, irritability and
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Associations of Behavioural and Psychological Symptoms of Dementia (BPSD) with use of acute healthcare and secondary mental health care services.
Behavioural and psychological symptoms of dementia increase the use of healthcare services and patients often present to services in crisis. This is distressing for patients and families and is expensive for
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Genomic influences on the trajectory of psychotic disorders
Better understanding the course of psychotic disorders will allow us to improve patient care; this project will combine genetic data with longitudinal electronic health records to more accurately predict outcomes in
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Assault hospitalisation in people with mental health conditions: a clinical epidemiological study of time trends, mortality and multimorbidity
People with mental health conditions are more likely to use hospital care (including emergency care) for assault, but changes over time (including during Covid) and impact on physical health(through accumulation of
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Ascertaining recurrent falls around the time of a first dementia diagnosis
Many people with dementia are at risk of injury from falls, partly because of advanced old age, partly because of other co-occurring physical health conditions, and partly because some types of
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Improving the ascertainment of treatment response in depression and psychosis
CRIS provides a valuable opportunity for ascertaining different responses to treatment in disorders such as depression, schizophrenia, and bipolar disorder. Methods have already been developed to ascertain when someone hasn't responded
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Defining cognitive profiles and trajectories of neurodegeneration with neurocomputational approaches
Progression of dementia is known to vary considerably between individuals.Using data from different public and private datasets, this project will investigate this variability within and across disorders.
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IM Clozapine Dose Concentration Analysis
Intramuscular (IM) clozapine has significant potential for the treatment of individuals with Treatment Resistant Schizophrenia (TRS), however it remains under-prescribed as data on its pharmacokinetics (PK) and clinical use is limited,
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