Search the CRIS Projects
Welcome to the CRIS project search area. As you will see below, there are a number of ways to find information about our CRIS projects. Simply add the criteria you are looking for into the relevant search field to see the relevant projects.
Please contact the CRIS Administrator for further details on existing projects or to apply to use CRIS for your own study. Email: cris.administrator@slam.nhs.uk
Antidepressant use in early dementia
Antidepressants are frequently prescribed to people who are developing dementia, but are not usually helpful for symptoms of dementia. We will look at data for people around the time of dementia
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Prevalence of attention deficit hyperactivity disorder in adults with Down syndrome in secondary mental health services
While attention deficit hyperactivity disorder (ADHD) is suspected to have increased prevalence in individuals with Down syndrome, there is limited research on the prevalence of ADHD in this population. The current
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Household stressors and mental health service use in Southeast London
Most studies of NHS mental health care inequalities in the UK focus only on characteristics of service users, i.e. there is limited/no information on local context. This is an important limitation
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Co-occurring mental disorders in children and adolescents with intellectual disabilities: A mixed-methods study assessing the effectiveness of psychological interventions in the context of the family system
Little is known about what routine psychological interventions are effective for children and adolescents with intellectual disabilities and how parental mental health can affect intervention outcomes of their children. This project
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Exploring the relationship between autism spectrum disorder and borderline personality disorder diagnoses in clinical practice: co-prevalence, timing and demographic factors
Autism Spectrum Disorder and Borderline Personality Disorder can have similar features and be difficult to differentiate clinically. We will assess the frequency and timing of these diagnoses among patients who have
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Evaluating the clinical effectiveness, acceptability and tolerability of pharmacological treatments of attention-deficit hyperactivity disorder in adults and young people with autism spectrum disorder: a retrospective cohort study.
There is a general lack of high quality evidence regarding the effectiveness and tolerability of medications for attention-deficit hyperactivity disorder (ADHD) when prescribed for people with autism spectrum disorder. We plan
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Management of Clozapine-associated Obsessive-Compulsive Symptoms (OCS): a descriptive study
In clinical practice it is well known that Clozapine can cause Obsessive-Compulsive Symptoms (OCS). This study will try to describe local clinical management of clozapine-associated OCS.
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Association between clinical phenotypes and mortality, acute and mental health hospitalisations among people with mental health problems
Symptoms may be more useful prognostic markers for mental illness than diagnoses. The aim of this study is to investigate whether and which symptom profiles are associated with mortality, physical health,
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Comparison of health outcomes among patients who are in community treatment orders (CTOs) receiving antipsychotic long-acting injections.
There is a particular interest, and some controversy, regarding the effectiveness of community treatment orders (CTOs) and antipsychotic long-acting injections (LAIs) on health outcomes e.g., relapse prevention for people with psychosis.
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Prognostic predictors of outcome following psychological treatment for anxiety or depression: a longitudinal statistical learning approach using electronic health record data
This project will explore clinical and demographic predictors of treatment response in patients with anxiety and depression who have received psychological therapy via the ‘Improving Access to Psychological Therapies’ (IAPT) service
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