CRIS Projects Details -
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CRIS Projects Details

Project Details

 

Improving agranulocytosis detection in patients treated with clozapine using machine learning

Lead Applicant Name :
Eromona Whiskey
Project Type :
Research
Approval Date :
12-Dec-2019
References :
Lay Summary :
Clozapine is the most effective antipsychotic in the treatment of refractory schizophrenia. Regular blood monitoring is mandatory during clozapine treatment because of the risk of blood cell side effects such as neutropenia and the more severe agranulocytosis. Unfortunately there is no way to determine if the reaction is mild or severe, and many patients have to discontinue treatment unnecessarily. The objective is to examine patterns in patients who develop agranulocytosis on treatment versus those patients who do not<br/>

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