Search the CRIS Projects
Welcome to the CRIS project search area. As you will see below, there are a number of ways to find information about our CRIS projects. Simply add the criteria you are looking for into the relevant search field to see the relevant projects.
Please contact the CRIS Administrator for further details on existing projects or to apply to use CRIS for your own study. Email: cris.administrator@slam.nhs.uk
Exploring the relationship between autism spectrum disorder and borderline personality disorder diagnoses in clinical practice: co-prevalence, timing and demographic factors
Autism Spectrum Disorder and Borderline Personality Disorder can have similar features and be difficult to differentiate clinically. We will assess the frequency and timing of these diagnoses among patients who have
Read more >
Evaluating the clinical effectiveness, acceptability and tolerability of pharmacological treatments of attention-deficit hyperactivity disorder in adults and young people with autism spectrum disorder: a retrospective cohort study.
There is a general lack of high quality evidence regarding the effectiveness and tolerability of medications for attention-deficit hyperactivity disorder (ADHD) when prescribed for people with autism spectrum disorder. We plan
Read more >
Management of Clozapine-associated Obsessive-Compulsive Symptoms (OCS): a descriptive study
In clinical practice it is well known that Clozapine can cause Obsessive-Compulsive Symptoms (OCS). This study will try to describe local clinical management of clozapine-associated OCS.
Read more >
Association between clinical phenotypes and mortality, acute and mental health hospitalisations among people with mental health problems
Symptoms may be more useful prognostic markers for mental illness than diagnoses. The aim of this study is to investigate whether and which symptom profiles are associated with mortality, physical health,
Read more >
Comparison of health outcomes among patients who are in community treatment orders (CTOs) receiving antipsychotic long-acting injections.
There is a particular interest, and some controversy, regarding the effectiveness of community treatment orders (CTOs) and antipsychotic long-acting injections (LAIs) on health outcomes e.g., relapse prevention for people with psychosis.
Read more >
Prognostic predictors of outcome following psychological treatment for anxiety or depression: a longitudinal statistical learning approach using electronic health record data
This project will explore clinical and demographic predictors of treatment response in patients with anxiety and depression who have received psychological therapy via the ‘Improving Access to Psychological Therapies’ (IAPT) service
Read more >
Clozapine-induced obsessive-compulsive symptoms
There is evidence that clozapine can cause obsessive-compulsive symptoms (OCS). Since clozapine is only prescribed for people with treatment resistant psychosis, a possible explanation is that treatment resistant psychosis could be
Read more >
Cannabis withdrawal induced psychosis
There have been several case reports that acute cannabis withdrawal can trigger psychotic illness. We hope to identify more cases and build on this literature.
Read more >
Insomnia and dementia outcomes
Sleep disturbance may be a feature of early dementia before diagnosis but little is known about its association with subsequent outcomes. This project will investigate recorded sleep difficulties around the time
Read more >
Reasons for and outcomes after lithium discontinuation in patients with bipolar or schizoaffective disorder. A case-register study based on the South London and Maudsley NHS Foundation Trust Clinical Record Interactive Search (CRIS) System
Lithium is one of the most effective treatments for bipolar disorders, but many people stop lithium because of adverse effects, thereby increasing their risk of relapse and even self-harm or suicide.
Read more >
Return to the NIHR Maudsley Biomedical Research Centre website.