Search the CRIS Projects
Welcome to the CRIS project search area. As you will see below, there are a number of ways to find information about our CRIS projects. Simply add the criteria you are looking for into the relevant search field to see the relevant projects.
Please contact the CRIS Administrator for further details on existing projects or to apply to use CRIS for your own study. Email: cris.administrator@slam.nhs.uk
Examining primary care data for early indicators for Parkinson’s related dementias
Parkinson’s related dementias (as dementia with Lewy bodies) are common but the diagnosis is often missed. We want to identify early signs of dementia with Lewy bodies in primary care records,
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Improving agranulocytosis detection in patients treated with clozapine using machine learning
Clozapine is the most effective antipsychotic in the treatment of refractory schizophrenia. Regular blood monitoring is mandatory during clozapine treatment because of the risk of blood cell side effects such as
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The interrelationships between receiving benefits, employment status and mental health: a data linkage project.
Annually, around 250,000 people claim unemployment or sickness related benefits because they have a mental health difficulty. This project will explore the interrelationships between receiving benefits, employment status, mental health difficulties,
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Exploring the linkage between UK census and CRIS
Errors in matching in data linkages may cause bias in the research being conducted using the linked data. We will explore missed matches and false match errors in the CRIS-Census linkage.
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Deriving occupations from CRIS electronic records from the free text
Details of patient’s occupations are often found in the free-text fields of CRIS electronic health records, therefore the extraction and analysis of occupation poses a challenge for researchers. We are developing
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Self-harm and suicidality amongst eating disorder patients: prevalence, risk factors and completed later suicide
Previous research shows that increased rates of self-harming and suicidality occur in those with an eating disorder diagnosis, therefore this study will look at how common self-harm and suicidality are amongst
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Perinatal stress and brain development
Maternal mental health problems during pregnancy have sometimes been linked to particular health conditions in the offspring; however, underlying reasons for this are poorly understood. This project aims to investigate whether
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Immune and psychiatric phenotype in schizophrenia and related disorders
Inflammatory bio-markers may be useful to identify which patients are unlikely to respond to conventional anti-psychotic treatment. This study will seek to characterize the immunological characteristics of patients experiencing acute psychosis
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Identifying clinical risk factors of Clozapine-induced Neutropenia/Agranulocytosis
The use of clozapine to treat treatment-resistant schizophrenia is limited due to the occurrence of low white blood cells (neutropenia), and the rare but fatal adverse drug event of agranulocytosis. This
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